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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKB
All Species:
35.76
Human Site:
S81
Identified Species:
56.19
UniProt:
P12277
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12277
NP_001814.2
381
42644
S81
C
V
A
G
D
E
E
S
Y
E
V
F
K
D
L
Chimpanzee
Pan troglodytes
XP_510185
464
51502
S164
C
V
A
G
D
E
E
S
Y
E
V
F
K
D
L
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
S81
C
V
A
G
D
E
E
S
Y
D
V
F
K
D
L
Dog
Lupus familis
XP_537561
394
44036
Y81
R
V
P
P
G
H
P
Y
I
M
T
V
G
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q04447
381
42695
S81
A
V
A
G
D
E
E
S
Y
D
V
F
K
D
L
Rat
Rattus norvegicus
P07335
381
42707
S81
A
V
A
G
D
E
E
S
Y
D
V
F
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
S74
D
P
N
Y
V
L
S
S
R
V
R
T
G
R
S
Chicken
Gallus gallus
P05122
381
42852
S81
C
V
A
G
D
E
E
S
Y
E
V
F
K
E
L
Frog
Xenopus laevis
NP_001080363
376
42223
V79
G
D
E
E
S
Y
E
V
F
K
D
L
F
D
P
Zebra Danio
Brachydanio rerio
NP_775329
381
42865
T81
C
V
A
G
D
E
E
T
Y
D
V
F
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
F78
D
A
E
A
Y
T
V
F
A
D
L
F
D
P
I
Honey Bee
Apis mellifera
O61367
355
39990
A78
A
E
A
Y
T
L
F
A
D
L
F
D
P
I
I
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
F79
D
A
E
S
Y
T
L
F
A
D
L
F
N
P
V
Sea Urchin
Strong. purpuratus
P18294
1174
130851
S495
M
V
A
G
D
E
E
S
Y
D
V
F
A
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
S81
A
V
A
G
D
E
E
S
Y
D
V
F
K
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
99.2
94.4
N.A.
96.5
96.5
N.A.
77.9
90.5
83.1
85.8
N.A.
42.7
40.9
37.7
22.4
Protein Similarity:
100
82.1
100
95.9
N.A.
98.6
98.4
N.A.
83.7
96.3
92.3
93.1
N.A.
59
58.7
55.9
28.1
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
86.6
N.A.
6.6
93.3
13.3
80
N.A.
6.6
6.6
6.6
73.3
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
6.6
100
26.6
100
N.A.
26.6
20
26.6
86.6
Percent
Protein Identity:
N.A.
96.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
14
67
7
0
0
0
7
14
0
0
0
7
0
0
% A
% Cys:
34
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
20
7
0
0
60
0
0
0
7
54
7
7
7
54
0
% D
% Glu:
0
7
20
7
0
60
67
0
0
20
0
0
0
14
0
% E
% Phe:
0
0
0
0
0
0
7
14
7
0
7
74
7
0
0
% F
% Gly:
7
0
0
60
7
0
0
0
0
0
0
0
14
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
0
54
0
0
% K
% Leu:
0
0
0
0
0
14
7
0
0
7
14
7
0
0
54
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
7
7
7
0
0
7
0
0
0
0
0
7
14
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
7
0
7
0
0
7
0
% R
% Ser:
0
0
0
7
7
0
7
60
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
7
14
0
7
0
0
7
7
0
0
0
% T
% Val:
0
67
0
0
7
0
7
7
0
7
60
7
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
14
7
0
7
60
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _